GALNS Antibody

• Catalog number
  bs-13269R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GALNS Primary Polyclonal Antibody
• Also known as
  GALNS PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GALNS
• Specificity
  This is a highly specific antibody against GALNS.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GALNS
• Gene ID number
  2588
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Chondroitinase is a 522 amino acid protein that localizes to the lysosome and functions as an exohydrolase that is essential for the degradation of glycosaminoglycans, keratan sulfate and chondroitin 6-sulfate. Using calcium as a cofactor, Chondroitinase, which exists as a disulfide linked oligomer, catalyzes the hydrolysis of the 6-sulfate group on target substrates. Defects in the gene encoding Chondroitinase are the cause of mucopolysaccharidosis type 4A (MPS4A), an autosomal recessive lysosomal storage disease that is characterized by the intracellular accumulation of keratan sulfate and chondroitin-6-sulfate and is associated with dental anomalies, short stature and, in some cases, death in the second or third decade of life.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Chondroitinase; Chondroitinsulfatase; FLJ00319; FLJ17434; FLJ42844; FLJ98217; Galactosamine N acetyl 6 sulfate sulfatase; Galactose 6 sulfate sulfatase; GALNAC6S; GalNAc6S sulfatase; GAS; mFLJ00319; MPS4A; N acetylgalactosamine 6 sulfatase; N acetylgalactosamine 6 sulfate sulfatase; GALNS_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  GALNS  
• Gene symbol
  GALNS
• Short name
  Anti-GALNS
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GALNS Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4122
• Gene
  GALNS
• Long gene name
  galactosamine (N-acetyl)-6-sulfatase
• Synonyms gene name
  • galactosamine (N-acetyl)-6-sulfate sulfatase
• Synonyms
  • GAS
  • GALNAC6S
  • GalN6S
• Synonyms name
  • Morquio syndrome
  • mucopolysaccharidosis type IVA
  • N-acetylgalactosamine-6-sulfatase
  • chondroitinase
  • chondroitinsulfatase
  • galactose-6-sulfate sulfatase
• GenBank acession
  • D17629
• Locus
  16q24.3
• Discovery year
  1992-02-21
• Entrez gene record
  2588
• Pubmed identfication
  • 1755850
• Classification
  • Sulfatases
• VEGA ID
  OTTHUMG00000137862

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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