FRMD8 Antibody

• Catalog number
  bs-8240R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FRMD8 Primary Polyclonal Antibody
• Also known as
  FRMD8 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FRMD8
• Specificity
  This is a highly specific antibody against FRMD8.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FRMD8
• Gene ID number
  83786
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  FERM domains are roughly 150 amino acids in length and are found in a number of cytoskeletal-associated proteins such as Ezrin, Radixin, Moesin and 4.1 (erythrocyte membrane protein band 4.1), where they provide a link between cytoskeletal signals and membrane dynamics. FRMD8 (FERM domain-containing protein 8), also known as FKSG44, is a 464 amino acid protein containing one FERM domain. Existing as two alternatively spliced isoforms, the gene encoding FRMD8 maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  FERM domain containing protein 8; FKSG44; FRMD8_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FRMD8  
• Gene symbol
  FRMD8
• Short name
  Anti-FRMD8
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FRMD8 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25462
• Gene
  FRMD8
• Long gene name
  FERM domain containing 8
• Synonyms
  • FLJ90369
  • FKSG44
  • iTAP
• Synonyms name
  • iRhom Tail-Associated Protein
• GenBank acession
  • AK074850
• Locus
  11q13.1
• Discovery year
  2007-08-14
• Entrez gene record
  83786
• Pubmed identfication
  • 29897336
• RefSeq identity
  • NM_031904
• Classification
  • FERM domain containing
• VEGA ID
  OTTHUMG00000166275

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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