FMR1 (508CT17.2.2) Monoclonal Antibody

• Catalog number
  bsm-51162M
• Price
  Please ask
• Size
  0.1ml

• Long name
  FMR1 (508CT17.2.2) Monoclonal Antibody
• Also known as
  FMR1 (508CT17.2.2) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FMR1
• Specificity
  This is a highly specific antibody against FMR1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  508CT17.2.2
• Source
  This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.
• Gene ID number
  2332
• Swiss Prot
  Q06787
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000-5000)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
• Purification method
  Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  POF; FMRP; POF1; FRAXA; Synaptic functional regulator FMR1; Fragile X mental retardation protein 1; Protein FMR-1; FMR1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  FMR1   508CT17   Monoclonal  
• Gene symbol
  FMR1-IT1, FMR1-AS1, FMR1
• Short name
  Anti-FMR1
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgM
• Alternative name
  FMR1 (508CT17.2.2) Monoclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:41333
• Gene
  FMR1-IT1
• Long gene name
  FMR1 intronic transcript 1
• Synonyms gene name
  • FMR1 intronic transcript 1 (non-protein coding)
• Locus
  Xq27.3
• Discovery year
  2011-05-19
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000046184

Gene info

• Identity
  HGNC:39081
• Gene
  FMR1-AS1
• Long gene name
  FMR1 antisense RNA 1
• Synonyms gene
  • FMR1AS
  • FMR1-AS
• Synonyms gene name
  • FMR1 antisense RNA (non-protein coding)
  • FMR1 antisense RNA 1 (non-protein coding)
  • FMR1 antisense RNA 1 (head to head)
• Synonyms
  • ASFMR1
  • FMR4
• Synonyms name
  • antisense fragile X mental retardation protein
• Locus
  Xq27.3
• Discovery year
  2010-10-05
• Entrez gene record
  100126270
• Pubmed identfication
  • 17921506
  • 18213394
• RefSeq identity
  • NR_024499
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000182466

Gene info

• Identity
  HGNC:3775
• Gene
  FMR1
• Long gene name
  FMRP translational regulator 1
• Synonyms gene
  • POF1
  • POF
• Synonyms gene name
  • premature ovarian failure 1
  • fragile X mental retardation 1
• Synonyms
  • FMRP
  • FRAXA
  • MGC87458
• GenBank acession
  • X69962
• Locus
  Xq27.3
• Discovery year
  1992-01-17
• Entrez gene record
  2332
• Pubmed identfication
  • 1572655
• RefSeq identity
  • NM_002024
• VEGA ID
  OTTHUMG00000022606
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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