FbxL12 Antibody
-
Catalog numberbs-8466R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameFbxL12 Primary Polyclonal Antibody
-
Also known asFbxL12 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenFbxL12
-
SpecificityThis is a highly specific antibody against FbxL12.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FbxL12
-
Gene ID number54850
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenF-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune responses, signaling cascades and developmental events) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for proteasomal degradation. FBL12 (F-box and leucine-rich repeat protein 12), also designated FBXL12, is a 326 amino acid protein that contains one F-box domain, five LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. FBL12 interacts with both Skp1 and CUL-1, and is encoded by a gene that maps to human chromosome 19p13.2.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesF box and leucine rich repeat protein 12; F box protein FBL12; F box/LRR repeat protein 12; FBXL 12; FLJ20188; FXL12_HUMAN.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolFBXL12P1, FBXL12
-
Short nameAnti-FbxL12
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameFbxL12 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameFBXL12 pseudogene 1
-
Locus
-
Discovery year2020-01-08
-
Entrez gene record
-
RefSeq identity
Gene info
-
Identity
-
Gene
-
Long gene nameF-box and leucine rich repeat protein 12
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-06-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- F-box and leucine rich repeat proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data