FAM126A/Hyccin Antibody

• Catalog number
  bs-11554R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FAM126A/Hyccin Primary Polyclonal Antibody
• Also known as
  FAM126A/Hyccin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FAM126A/Hyccin
• Specificity
  This is a highly specific antibody against FAM126A/Hyccin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hyccin
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Hyccin is a 521 amino acid cytoplasmic protein that is widely expressed with highest levels found in heart, brain, placenta, spleen and testis. Belonging to the FAM126 family, hyccin may play a role in the ∫-catenin/Lef signaling pathway. Hyccin is likely involved in the process of myelination of the central and peripheral nervous system. Defects in the gene encoding hyccin are the cause of leukodystrophy hypomyelinating type 5 (HLD5), which is characterized by congenital cataract, progressive neurologic impairment and diffuse myelin deficiency. Individuals affected by HLD5 experience progressive pyramidal and cerebellar dysfunction along with muscle weakness in the lower limbs. Hyccin exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 7.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Down regulated by Ctnnb1 a; Down regulated by CTNNB1 protein A; Down-regulated by CTNNB1 protein A; DRCTNNB1A; FAM126A; Family with sequence similarity 126 member A; HCC; HLD5; HYCC1; HYCCI_HUMAN antibody Hyccin; Protein FAM126A.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FAM126A/Hyccin  
• Gene symbol
  FAM126A
• Short name
  Anti-FAM126A/Hyccin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FAM126A/Hyccin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24587
• Gene
  FAM126A
• Long gene name
  family with sequence similarity 126 member A
• Synonyms gene name
  • family with sequence similarity 126, member A
• Synonyms
  • DRCTNNB1A
  • HCC
  • HYCC1
  • hyccin
• Synonyms name
  • down regulated by Ctnnb1, a
• GenBank acession
  • BC018710
• Locus
  7p15.3
• Discovery year
  2006-09-06
• Entrez gene record
  84668
• Pubmed identfication
  • 29229838
  • 10910037
  • 16951682
  • 26571211
• RefSeq identity
  • NM_032581
• Classification
  • PI4KA lipid kinase complex
• VEGA ID
  OTTHUMG00000128435

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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