FAIM3 Antibody

• Catalog number
  bs-7527R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FAIM3 Primary Polyclonal Antibody
• Also known as
  FAIM3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FAIM3
• Specificity
  This is a highly specific antibody against FAIM3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  100-150/390
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FAIM3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.Tissue specificity: Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Faim3;FAIM3_HUMAN;Fas apoptotic inhibitory molecule 3;Fc mu receptor;R;IgM Fc receptor;Immunoglobulin mu Fc receptor;Regulator of Fas induced apoptosis;Regulator of Fas-induced apoptosis Toso;TOSO.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FAIM3  
• Gene symbol
  FCMR
• Short name
  Anti-FAIM3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FAIM3 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  Fas apoptotic inhibitory molecule 3, FCMR and TOSO, FAIM3 and IDBG-106292 and ENSG00000162894 and 9214, Extracellular, Faim3 and IDBG-190537 and ENSMUSG00000042474 and 69169, FAIM3 and IDBG-629197 and ENSBTAG00000019796 and 511564

Gene info

• Identity
  HGNC:14315
• Gene
  FCMR
• Long gene name
  Fc fragment of IgM receptor
• Synonyms gene
  • FAIM3
• Synonyms gene name
  • Fas apoptotic inhibitory molecule 3
• Synonyms
  • TOSO
• GenBank acession
  • AF057557
• Locus
  1q32.1
• Discovery year
  2005-04-04
• Entrez gene record
  9214
• Pubmed identfication
  • 9586636
  • 1563211
  • 25888699
• RefSeq identity
  • NM_005449
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000036457

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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