EYA2 Antibody
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Catalog numberbs-13125R
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PricePlease ask
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Size0.1ml
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Long nameEYA2 Primary Polyclonal Antibody
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Also known asEYA2 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenEYA2
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SpecificityThis is a highly specific antibody against EYA2.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EYA2
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Gene ID number2139
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenA gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesEAB 1; EAB1; EYA 2; EYA2; EYA2_HUMAN; eyes absent 2 homolog Drosophila; Eyes absent homolog 2; Translation of this uORF probably lowers the translation efficiency of EYA2.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolEYA2
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Short nameAnti-EYA2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameEYA2 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targeteyes absent homolog 2 (Drosophila), EAB1, EYA2 and IDBG-79457 and ENSG00000064655 and 2139, protein binding, nuclei, Eya2 and IDBG-212752 and ENSMUSG00000017897 and 14049, EYA2 and IDBG-643097 and ENSBTAG00000013336 and 615264
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Gene info
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Identity
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Gene
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Long gene nameEYA transcriptional coactivator and phosphatase 2
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Synonyms gene name
- eyes absent (Drosophila) homolog 2
- eyes absent homolog 2 (Drosophila)
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Synonyms
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Locus
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Discovery year1997-06-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EYA transcriptional coactivator and phosphatases
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data