Exportin 5 Antibody

• Catalog number
  bs-11219R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Exportin 5 Primary Polyclonal Antibody
• Also known as
  Exportin 5 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Exportin 5
• Specificity
  This is a highly specific antibody against Exportin 5.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Exportin 5
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Exportin 5 (XPO5) is a member of the importin β family of proteins and functions in tRNA export in a sequence dependent fashion. More recently, it has been shown to export pre-miRNA by a RanGTPase-driven process from the nucleus to the cytoplasm, where pre-miRNA processing occurs to produce mature miRNAs. Study of the miRNA biosynthesis pathway is essential in understanding the process of oncogenesis as global downregulation of miRNAs and the resulting alterations in the expression of tumor suppressor and oncogenic proteins is a common phenotype of cancers cells . Research studies have shown disruption of exportin 5 functions in many types of cancers including breast and lung, where pre-miRNA accumulates in the nucleus and miRNA maturation is impaired.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Exp 5; Exp5; Exportin 5; Exportin-5; Exportin5; FLJ14239; FLJ32057; FLJ45606; KIAA1291; Ran binding protein 21; Ran-binding protein 21; Ranbp 21; Ranbp21; Xpo 5; xpo5; XPO5_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Exportin  
• Gene symbol
  XPO5
• Short name
  Anti-Exportin 5
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Exportin 5 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17675
• Gene
  XPO5
• Long gene name
  exportin 5
• Synonyms
  • KIAA1291
• GenBank acession
  • AB033117
• Locus
  6p21.1
• Discovery year
  2003-03-10
• Entrez gene record
  57510
• Pubmed identfication
  • 11777942
  • 12426392
• RefSeq identity
  • NM_020750
• Classification
  • Exportins
• VEGA ID
  OTTHUMG00000014742

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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