ETS1 associated protein II Antibody
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Catalog number
bs-5164R
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Price
Please ask
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Size
0.1ml
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Long name
ETS1 associated protein II Antibody
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Also known as
ETS1 associated protein II Antibody
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
ETS1 associated protein II
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Specificity
This is a highly specific antibody against ETS1 associated protein II.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ETS1 associated protein II/EAPII
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
EAP 2; EAP II; EAP2; EAPII; ETS 1 associated protein 2; ETS 1 associated protein II; ETS1 associated protein 2; ETS1-associated protein 2; ETS1-associated protein II; tdp2; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TTRAP; TYDP2_HUMAN; Tyr DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; Tyrosyl DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; 5''-Tyr-DNA phosphodiesterase; 5''-tyrosyl-DNA phosphodiesterase; AD 022; AD022; MGC111021; MGC9099.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
ETS1-AS1, ETS1
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Short name
Anti-ETS1 associated protein II
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
ETS1 associated protein II Antibody
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Alternative technique
antibodies
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Alternative to gene target
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian), ETS-1 and EWSR2 and p54, ETS1 and IDBG-75897 and ENSG00000134954 and 2113, sequence-specific DNA binding, nuclei, Ets1 and IDBG-147548 and ENSMUSG00000032035 and 23871, ETS1 and IDBG-642787 and ENSBTAG00000002341 and 540313
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Gene info
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Identity
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Gene
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Long gene name
ETS1 antisense RNA 1
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Synonyms
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Synonyms name
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Locus
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Discovery year
2018-07-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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