ET-2/Endothelin 2 Antibody
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Catalog number
bs-11280R
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Price
Please ask
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Size
0.1ml
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Long name
ET-2/Endothelin 2 Primary Polyclonal Antibody
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Also known as
ET-2/Endothelin 2 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
ET-2/Endothelin 2
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Specificity
This is a highly specific antibody against ET-2/Endothelin 2.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Endolin 2
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Tested Applications
IHC-P, IF(IHC-P)
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Recommended dilutions
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor type B (ETBR) and, through this interaction, mediates the maturation of enteric neurons and melanocytes. Although ET-3 is expressed as a 238 amino acid peptide, it is post-translationally modified to produce a short active isoform and a long inactive isoform. Defects in the gene encoding ET-3 are the cause of a variety of disorders, including Hirschsprung disease type 1 (HSCR1), congenital central hypoventilation syndrome (CCHS) and Waardenburg syndrome type IV (WS4).
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
EDN2; EDN2_HUMAN; Endothelin 2; Endothelin-2; ET 2; ET-2; ET2; PPET2; Preproendothelin 2; Preproendothelin-2.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
EDN2, PCYT2, EDNRA, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
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Short name
Anti-ET-2/Endothelin 2
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
ET-2/Endothelin 2 Polyclonal Antibody
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
endothelin 2
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-09-06
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Entrez gene record
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
microRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
microRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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