Ephrin A1 Antibody

• Catalog number
  bs-1763R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Ephrin A1 Antibody
• Also known as
  Ephrin A1 Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Ephrin A1
• Specificity
  This is a highly specific antibody against Ephrin A1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  140-182/205
• Subcellular location
  Secreted, Cell membrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ephrin A1
• Gene ID number
  2041
• Swiss Prot
  P21709
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  EPH; EPHT; EPHT1; Ephrin type-A receptor 1; hEpha1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH; EPHA1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Ephrin  
• Gene symbol
  EFNA1
• Short name
  Anti-Ephrin A1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Ephrin A1 Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3221
• Gene
  EFNA1
• Long gene name
  ephrin A1
• Synonyms gene
  • TNFAIP4
  • EPLG1
• Synonyms gene name
  • ephrin-A1
• Synonyms
  • LERK1
  • ECKLG
  • GMAN
• Synonyms name
  • EPH-related receptor tyrosine kinase ligand 1
  • Tumor necrosis factor alpha-induced protein 4
  • gastric cancer metastasis associated long noncoding RNA
• Locus
  1q22
• Discovery year
  1992-10-20
• Entrez gene record
  1942
• Pubmed identfication
  • 2233719
  • 8660976
• RefSeq identity
  • NM_004428
• Classification
  • Ephrins
• VEGA ID
  OTTHUMG00000035312

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products