EML4 Antibody

• Catalog number
  bs-9803R
• Price
  Please ask
• Size
  0.1ml

• Long name
  EML4 Primary Polyclonal Antibody
• Also known as
  EML4 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  EML4
• Specificity
  This is a highly specific antibody against EML4.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EML4/C2orf180
• Gene ID number
  27436
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML4 (Echinoderm microtubule-associated protein-like 4), also known as EMAPL4, ELP120, C2orf2 or ROPP120, is a 981 amino acid cytoplasmic protein that contains nine WD repeats. Expressed at high levels during mitosis, EML4 is thought to modify the assembly dynamics of microtubules, specifically altering microtubules to become longer and more flexible. Due to a chromosomal inversion with chromosome 2p, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  EML4; EML-4; C2orf2; Echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; ELP 120; ELP120; EMAL4_HUMAN; EMAP 4; EMAP-4; EMAP4; EML 4; eml4; Restrictedly overexpressed proliferation associated protein; Restrictedly overexpressed proliferation-associated protein; Ropp 120; ROPP120.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  EML4  
• Gene symbol
  EML4-AS1, EML4
• Short name
  Anti-EML4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  EML4 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40112
• Gene
  EML4-AS1
• Long gene name
  EML4 antisense RNA 1
• Locus
  2p21
• Discovery year
  2019-07-25
• Entrez gene record
  102723824
• RefSeq identity
  • NR_110584
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:1316
• Gene
  EML4
• Long gene name
  EMAP like 4
• Synonyms gene
  • C2orf2
• Synonyms gene name
  • echinoderm microtubule associated protein like 4
• Synonyms
  • ROPP120
  • ELP120
• GenBank acession
  • AF177377
• Locus
  2p21
• Discovery year
  2000-01-31
• Entrez gene record
  27436
• RefSeq identity
  • NM_019063
• Classification
  • WD repeat domain containing
  • EMAP like
• VEGA ID
  OTTHUMG00000128603

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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