Emerin Antibody

• Catalog number
  bs-6660R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Emerin Primary Polyclonal Antibody
• Also known as
  Emerin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Emerin
• Specificity
  This is a highly specific antibody against Emerin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Emerin
• Gene ID number
  2010
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.Tissue specificity; Skeletal muscle, heart, colon, testis, ovary and pancreas.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  EDMD; EMD; EMD_HUMAN; Emerin; Emery Dreuss muscular dystrophy; STA.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Emerin  
• Gene symbol
  EMD, LEMD2
• Short name
  Anti-Emerin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Emerin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3331
• Gene
  EMD
• Long gene name
  emerin
• Synonyms gene name
  • Emery-Dreifuss muscular dystrophy
• Synonyms
  • STA
  • LEMD5
• Synonyms name
  • LEM domain containing 5
• GenBank acession
  • X82434
• Locus
  Xq28
• Discovery year
  2001-06-22
• Entrez gene record
  2010
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000033186
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • UMD Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • Global Variome shared LOVD
  • LRG_745

Gene info

• Identity
  HGNC:21244
• Gene
  LEMD2
• Long gene name
  LEM domain nuclear envelope protein 2
• Synonyms gene name
  • LEM domain containing 2
• Synonyms
  • dJ482C21.1
  • NET25
  • LEM2
• Synonyms name
  • lamina-associated polypeptide-emerin-MAN1 domain containing 2
• Locus
  6p21.31
• Discovery year
  2003-05-29
• Entrez gene record
  221496
• Pubmed identfication
  • 16339967
  • 28056360
  • 28242692
  • 31147383
• RefSeq identity
  • NM_181336
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000014535

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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