Elongin B Antibody
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Catalog numberbs-5136R
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PricePlease ask
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Size0.1ml
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Long nameElongin B Primary Polyclonal Antibody
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Also known asElongin B PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenElongin B
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SpecificityThis is a highly specific antibody against Elongin B.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Elongin B
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Gene ID number6923
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenTCEB2 (Elongin B), is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesEloB; Elongin 18 kDa subunit; Elongin B; RNA polymerase II transcription factor SIII subunit B; SIII p18; TCEB 2; Transcription elongation factor B SIII polypeptide 2; EloB; ELOB_HUMAN; Elongin-B; RNA polymerase II transcription factor SIII p18 subunit; RNA polymerase II transcription factor SIII subunit B; SIII; Tceb2; Transcription elongation factor B SIII polypeptide 2; Transcription elongation factor B polypeptide 2.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolELOB, ELOBP3, ELOA2
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Short nameAnti-Elongin B
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameElongin B Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameelongin B
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Synonyms gene
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Synonyms gene name
- transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- transcription elongation factor B subunit 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-09-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Elongin complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameelongin B pseudogene 3
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Synonyms gene
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Synonyms gene name
- transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) pseudogene 3
- transcription elongation factor B subunit 2 pseudogene 3
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Locus
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Discovery year2011-03-24
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Entrez gene record
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameelongin A2
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Synonyms gene
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Synonyms gene name
- transcription elongation factor B polypeptide 3B (elongin A2)
- transcription elongation factor B subunit 3B
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Elongin complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data