ELL Antibody

• Catalog number
  bs-8515R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ELL Primary Polyclonal Antibody
• Also known as
  ELL PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ELL
• Specificity
  This is a highly specific antibody against ELL.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ELL
• Gene ID number
  8178
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ELL_HUMAN; Eleven nineteen lysine rich leukemia gene; Eleven-nineteen lysine-rich leukemia protein; ELL1; elongation factor RNA polymerase II; Men; RNA polymerase II elongation factor; RNA polymerase II elongation factor ELL.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ELL  
• Gene symbol
  ELL
• Short name
  Anti-ELL
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ELL Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23114
• Gene
  ELL
• Long gene name
  elongation factor for RNA polymerase II
• Synonyms gene
  • C19orf17
• Synonyms gene name
  • chromosome 19 open reading frame 17
  • elongation factor RNA polymerase II
• Synonyms
  • Men
  • ELL1
  • PPP1R68
• Synonyms name
  • protein phosphatase 1, regulatory subunit 68
  • eleven-nineteen lysine-rich leukemia gene
• GenBank acession
  • U16282
• Locus
  19p13.11
• Discovery year
  2003-09-17
• Entrez gene record
  8178
• Pubmed identfication
  • 7991593
  • 8596958
• RefSeq identity
  • NM_006532
• Classification
  • Super elongation complex
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000183364

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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