Dysferlin Antibody

• Catalog number
  bs-2429R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Dysferlin Primary Polyclonal Antibody
• Also known as
  Dysferlin PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Dysferlin
• Specificity
  This is a highly specific antibody against Dysferlin.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dysferlin
• Gene ID number
  8291
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  DMAT; DYSF; Dysferlin Dystrophy associated fer 1 like protein Fer 1 like protein 1; Dysferlin limb girdle muscular dystrophy 2B autosomal recessive; Dysferlin limb girdle muscular dystrophy 2B; Dystrophy associated fer 1 like 1; Dystrophy associated fer 1 like protein; Dystrophy associated fer1 like 1; Dystrophy associated fer1 like protein; Fer 1 like protein 1; Fer1 like protein 1; FER1L1; FLJ00175; FLJ90168; LGMD 2B; LGMD2B; Limb girdle muscular dystrophy 2B autosomal recessive ; Limb girdle muscular dystrophy 2B; Miyoshi myopathy; MM; DYSF_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Dysferlin  
• Gene symbol
  PPP1R27, DYSF
• Short name
  Anti-Dysferlin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Dysferlin Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16813
• Gene
  PPP1R27
• Long gene name
  protein phosphatase 1 regulatory subunit 27
• Synonyms gene
  • DYSFIP1
• Synonyms gene name
  • dysferlin-interacting protein 1 (toonin)
  • dysferlin interacting protein 1 (toonin)
  • dysferlin interacting protein 1
  • protein phosphatase 1, regulatory subunit 27
• Synonyms
  • toonin
• GenBank acession
  • AF434846
• Locus
  17q25.3
• Discovery year
  2001-10-16
• Entrez gene record
  116729
• RefSeq identity
  • NM_001007533
• Classification
  • Ankyrin repeat domain containing
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000177916

Gene info

• Identity
  HGNC:3097
• Gene
  DYSF
• Long gene name
  dysferlin
• Synonyms gene
  • LGMD2B
• Synonyms gene name
  • limb girdle muscular dystrophy 2B (autosomal recessive)
• Synonyms
  • FER1L1
• Synonyms name
  • fer-1-like family member 1
• GenBank acession
  • AF075575
• Locus
  2p13.2
• Discovery year
  1994-03-24
• Entrez gene record
  8291
• Pubmed identfication
  • 8320700
• RefSeq identity
  • NM_003494
• Classification
  • Ferlin family
• VEGA ID
  OTTHUMG00000129757
• Locus Specific Databases
  • Leiden Muscular Dystrophy Pages
  • Leiden Muscular Dystrophy pages
  • LRG_845

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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