DYRK2 Antibody

• Catalog number
  bs-12332R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DYRK2 Primary Polyclonal Antibody
• Also known as
  DYRK2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DYRK2
• Specificity
  This is a highly specific antibody against DYRK2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DYRK2
• Gene ID number
  8445
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (1–3). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  1810038L18Rik; Dual specicity tyrosine Y phosphorylation regulated kinase 2; Dual specicity tyrosine phosphorylation regulated kinase 2; Dual specicity tyrosine-phosphorylation-regulated kinase 2; DYRK2; DYRK2_HUMAN; EC 2.7.12.1; FLJ21217; FLJ21365.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DYRK2  
• Gene symbol
  DYRK2
• Short name
  Anti-DYRK2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DYRK2 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, DYRK2 and IDBG-45841 and ENSG00000127334 and 8445, transferase activity, nuclei, Dyrk2 and IDBG-192216 and ENSMUSG00000028630 and 69181, DYRK2 and IDBG-634243 and ENSBTAG00000007256 and 514916

Gene info

• Identity
  HGNC:3093
• Gene
  DYRK2
• Long gene name
  dual specificity tyrosine phosphorylation regulated kinase 2
• Synonyms gene name
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
  • dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2
• GenBank acession
  • Y09216
• Locus
  12q15
• Discovery year
  1998-10-29
• Entrez gene record
  8445
• Pubmed identfication
  • 9748265
• VEGA ID
  OTTHUMG00000169089

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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