DUSP3 Antibody
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Catalog numberbs-6246R
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PricePlease ask
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Size0.1ml
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Long nameDUSP3 Primary Polyclonal Antibody
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Also known asDUSP3 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenDUSP3
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SpecificityThis is a highly specific antibody against DUSP3.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUSP3
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Gene ID number1845
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesDual specicity phosphatase 3; Dual specicity protein phosphatase 3; Dual specicity protein phosphatase VHR; DUS3_HUMAN; DUSP3; Serine/threonine specic protein phosphatase; Vaccinia H1-related phosphatase; Vaccinia virus phosphatase VH1 related; VHR.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolDUSP3
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Short nameAnti-DUSP3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameDUSP3 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetdual specificity phosphatase 3, VHR, DUSP3 and IDBG-52945 and ENSG00000108861 and 1845, MAP kinase phosphatase activity, nuclei, Dusp3 and IDBG-212400 and ENSMUSG00000003518 and 72349, DUSP3 and IDBG-640759 and ENSBTAG00000003966 and 615432
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Gene info
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Identity
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Gene
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Long gene namedual specificity phosphatase 3
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Synonyms gene
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Synonyms gene name
- vaccinia virus phosphatase VH1-related
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GenBank acession
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Locus
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Discovery year1994-05-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Atypical dual specificity phosphatases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data