DUOXA2 Antibody

• Catalog number
  bs-8863R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DUOXA2 Primary Polyclonal Antibody
• Also known as
  DUOXA2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DUOXA2
• Specificity
  This is a highly specific antibody against DUOXA2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUOXA2
• Gene ID number
  405753
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family. Expressed specifically in thyroid and salivary glands, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH). Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth. The gene encoding DUOXA2 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Dual oxidase activator 2; Dual oxidase maturation factor 2; SIMNIPHOM; TDH5; DOXA2_HUMAN; Dual oxidase maturation factor-2; Dual oxidase activator 2..
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DUOXA2  
• Gene symbol
  DUOXA2
• Short name
  Anti-DUOXA2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DUOXA2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:32698
• Gene
  DUOXA2
• Long gene name
  dual oxidase maturation factor 2
• GenBank acession
  • BX537581
• Locus
  15q21.1
• Discovery year
  2006-05-16
• Entrez gene record
  405753
• Pubmed identfication
  • 16651268
• RefSeq identity
  • NM_207581
• VEGA ID
  OTTHUMG00000131354

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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