DR1 protein Antibody

• Catalog number
  bs-9055R
• Price
  Please ask
• Size
  0.1ml

• Long name
  DR1 protein Primary Polyclonal Antibody
• Also known as
  DR1 protein PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  DR1 protein
• Specificity
  This is a highly specific antibody against DR1 protein.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR1 protein
• Gene ID number
  10589
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Dr1 protein; NC2; Negative cofactor 2 beta; Down regulator of transcription 1; Down regulator of transcription 1 TBP binding; Down-regulator of transcription 1; DR 1; Dr1; NC 2; NC2 beta; NC2-beta; NC2B_HUMAN; Negative co factor 2; Negative cofactor 2; Negative cofactor 2-beta; Protein Dr1; TATA binding protein associated phosphoprotein; TATA-binding protein-associated phosphoprotein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DR1   protein  
• Gene symbol
  DR1, CHRFAM7A
• Short name
  Anti-DR1 protein
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  DR1 protein Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3017
• Gene
  DR1
• Long gene name
  down-regulator of transcription 1
• Synonyms gene name
  • down-regulator of transcription 1, TBP-binding (negative cofactor 2)
• Synonyms
  • NC2-BETA
  • NC2B
  • NCB2
• Synonyms name
  • negative cofactor 2
  • negative cofactor 2 beta
• GenBank acession
  • M97388
• Locus
  1p22.1
• Discovery year
  1996-07-11
• Entrez gene record
  1810
• Pubmed identfication
  • 1339312
  • 9040789
• RefSeq identity
  • NM_001938
• Classification
  • ATAC complex
• VEGA ID
  OTTHUMG00000010862

Gene info

• Identity
  HGNC:15781
• Gene
  CHRFAM7A
• Long gene name
  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
• Synonyms gene name
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
• Synonyms
  • D-10
  • CHRNA7-DR1
• GenBank acession
  • AF029838
• Locus
  15q13.2
• Discovery year
  2001-06-29
• Entrez gene record
  89832
• Pubmed identfication
  • 11829490
• RefSeq identity
  • NM_148911
• VEGA ID
  OTTHUMG00000175645

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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