Dio3 Antibody

• Catalog number
  bs-3902R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Dio3 Primary Polyclonal Antibody
• Also known as
  Dio3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Dio3
• Specificity
  This is a highly specific antibody against Dio3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dio3
• Gene ID number
  1735
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Type 3 DI; D3; 5DIII; Deiodinase iodothyronine type 3; Deiodinase iodothyronine type III; Dio 3; DIOIII; MGC124117; MGC124118; TXDI3; Type III 5' deiodinase; Type III iodothyronine deiodinase.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Dio3  
• Gene symbol
  DIO3, DIO3OS
• Short name
  Anti-Dio3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Dio3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2885
• Gene
  DIO3
• Long gene name
  iodothyronine deiodinase 3
• Synonyms gene
  • TXDI3
• Synonyms gene name
  • deiodinase, iodothyronine type III
• Synonyms name
  • thyroxine 5-deiodinase
  • selenoprotein DIO3
• GenBank acession
  • S79854
• Locus
  14q32.31
• Discovery year
  1996-04-09
• Entrez gene record
  1735
• Pubmed identfication
  • 9787088
  • 7593630
• RefSeq identity
  • NM_001362
• Classification
  • Selenoproteins
• VEGA ID
  OTTHUMG00000160681

Gene info

• Identity
  HGNC:20348
• Gene
  DIO3OS
• Long gene name
  DIO3 opposite strand upstream RNA
• Synonyms gene
  • C14orf134
• Synonyms gene name
  • chromosome 14 open reading frame 134
  • deiodinase, iodothyronine, type III opposite strand
  • DIO3 opposite strand/antisense RNA
  • DIO3 opposite strand/antisense RNA (head to head)
• Synonyms
  • NCRNA00041
  • DIO3-AS1
• Synonyms name
  • non-protein coding RNA 41
• GenBank acession
  • AF305836
• Locus
  14q32.31
• Discovery year
  2003-01-28
• Entrez gene record
  64150
• Pubmed identfication
  • 14962667
• RefSeq identity
  • NR_002770
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000171682

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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