CYP8A1/PTGIS Antibody

• Catalog number
  bs-3677R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CYP8A1/PTGIS Primary Polyclonal Antibody
• Also known as
  CYP8A1/PTGIS PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CYP8A1/PTGIS
• Specificity
  This is a highly specific antibody against CYP8A1/PTGIS.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
• Gene ID number
  5740
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 prostacyclin synthase; Prostaglandin I2 synthase; PTGI.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CYP8A1/PTGIS  
• Gene symbol
  PTGIS
• Short name
  Anti-CYP8A1/PTGIS
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CYP8A1/PTGIS Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  prostaglandin I2 (prostacyclin) synthase, CYP8 and CYP8A1 and PGIS and PTGI, PTGIS and IDBG-80513 and ENSG00000124212 and 5740, oxidoreductase activity, nuclei, Ptgis and IDBG-213024 and ENSMUSG00000017969 and 19223, PTGIS and IDBG-643178 and ENSBTAG00000017537 and 101910090,282021

Gene info

• Identity
  HGNC:9603
• Gene
  PTGIS
• Long gene name
  prostaglandin I2 synthase
• Synonyms gene name
  • prostaglandin I2 (prostacyclin) synthase
• Synonyms
  • PGIS
  • CYP8A1
• Synonyms name
  • cytochrome P450, family 8, subfamily A, polypeptide 1
  • prostacyclin synthase
• Locus
  20q13.13
• Discovery year
  1994-07-28
• Entrez gene record
  5740
• Pubmed identfication
  • 8812456
• Classification
  • Cytochrome P450 family 8
• VEGA ID
  OTTHUMG00000033077
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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