CXCR4 Antibody
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Catalog numberbs-20318R
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PricePlease ask
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Size0.1ml
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Long nameCXCR4 Primary Polyclonal Antibody
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Also known asCXCR4 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenCXCR4
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SpecificityThis is a highly specific antibody against CXCR4.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range170-190/359
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Subcellular locationExtracellular, Helical
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SourceKLH conjugated synthetic peptide derived from mouse CXCR4
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Gene ID number12767
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Swiss ProtP70658
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Tested ApplicationsWB
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Recommended dilutionsWB(1:100-1000)
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Cross reactivityMouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenBinds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesCD184; LESTR; Sdf1r; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor; Pre-B-cell-derived chemokine receptor; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Cxcr4
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCXCR4
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Short nameAnti-CXCR4
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameCXCR4 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetchemokine (C-X-C motif) receptor 4, CD184 and D2S201E and FB22 and HM89 and HSY3RR and LAP-3 and LAP3 and LCR1 and LESTR and NPY3R and NPYR and NPYRL and NPYY3R and WHIM, CXCR4 and IDBG-71032 and ENSG00000121966 and 7852, ubiquitin binding, Cell surfaces, Cxcr4 and IDBG-189999 and ENSMUSG00000045382 and 12767, CXCR4 and IDBG-642187 and ENSBTAG00000001060 and 281736
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Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine receptor 4
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Synonyms gene name
- chemokine (C-X-C motif), receptor 4 (fusin)
- chemokine (C-X-C motif) receptor 4
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-17
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Entrez gene record
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Pubmed identfication
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Classification
- C-X-C motif chemokine receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data