CSTF3/CSTF77 Antibody

• Catalog number
  bs-12935R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CSTF3/CSTF77 Primary Polyclonal Antibody
• Also known as
  CSTF3/CSTF77 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CSTF3/CSTF77
• Specificity
  This is a highly specific antibody against CSTF3/CSTF77.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSTF3/CSTF77
• Gene ID number
  1479
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors. The first step, endonucleolytic cleavage of polyadenylation substrates, requires CstF (cleavage stimulation factor), a heterotrimer that is composed of three distinct subunits. Heterotrimeric CstF recognizes GU- and U-rich sequences located downstream of the polyadenylation site on RNA. CstF-77 (cleavage stimulation factor, 77 kDa subunit), also known as CstF3, is one of the three subunits comprising CstF. It can exist as a homodimer and functions as the bridge, directly interacting with the other two CstF subunits, namely CstF-64 and CstF-50. CstF-77 is highly conserved among eukaryotes. It contains an Alpha-helical structure with 11 HAT (Half-a-TPR-containing) repeats and is essential for CstF assembly. In addition, CstF-77 is capable of interacting with CPSF1 and FCP1, other factors involved in polyadenylation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CF 1 77 kDa subunit; Cleavage stimulation factor 77 kDa subunit; Cleavage stimulation factor subunit 3; Cleavage stimulation factor subunit 3 isoform 1; CSTF 3; CSTF 77; CSTF 77 kDa subunit; CSTF77; MGC117398; MGC43001; MGC75122; CSTF3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CSTF3/CSTF77  
• Gene symbol
  CSTF3-DT, CSTF3
• Short name
  Anti-CSTF3/CSTF77
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CSTF3/CSTF77 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:27882
• Gene
  CSTF3-DT
• Long gene name
  CSTF3 divergent transcript
• Synonyms gene
  • CSTF3-AS1
• Synonyms gene name
  • CSTF3 antisense RNA 1 (head to head)
• Locus
  11p13
• Discovery year
  2013-01-23
• Entrez gene record
  338739
• Pubmed identfication
  • 12477932
• RefSeq identity
  • NR_034027
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000166243

Gene info

• Identity
  HGNC:2485
• Gene
  CSTF3
• Long gene name
  cleavage stimulation factor subunit 3
• Synonyms gene name
  • cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kD
  • cleavage stimulation factor, 3' pre-RNA, subunit 3
• Synonyms
  • CstF-77
• GenBank acession
  • U15782
• Locus
  11p13
• Discovery year
  1995-01-16
• Entrez gene record
  1479
• Pubmed identfication
  • 7984242
• RefSeq identity
  • NM_001326
• Classification
  • Cleavage stimulation factor subunits
• VEGA ID
  OTTHUMG00000166268

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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