CRF Antibody

• Catalog number
  bs-0246R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CRF Primary Polyclonal Antibody
• Also known as
  CRF PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CRF
• Specificity
  This is a highly specific antibody against CRF.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRF
• Gene ID number
  1392
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Corticoliberin; Corticoliberin precursor; Corticotropin releasing factor; Corticotropin releasing hormone; Corticotropin releasing hormone deficiency included; crf; crh; crh deficiency included; corticoliberin preproprotein; CRF_HUMAN; Corticotropin-releasing factor; CRF; CRH; Corticotropin-releasing hormone.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CRF  
• Gene symbol
  CRHR2, CRH, CRHBP, CRHR1, C1QL1
• Short name
  Anti-CRF
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CRF Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2358
• Gene
  CRHR2
• Long gene name
  corticotropin releasing hormone receptor 2
• Synonyms
  • CRF2
  • CRF-RB
  • HM-CRF
• Locus
  7p14.3
• Discovery year
  1996-12-18
• Entrez gene record
  1395
• Pubmed identfication
  • 8536644
• Classification
  • Corticotropin releasing hormone receptors
• VEGA ID
  OTTHUMG00000023218

Gene info

• Identity
  HGNC:2355
• Gene
  CRH
• Long gene name
  corticotropin releasing hormone
• Synonyms
  • CRF
  • CRH1
• Synonyms name
  • corticotropin-releasing factor
  • corticoliberin
• Locus
  8q13.1
• Discovery year
  1988-08-31
• Entrez gene record
  1392
• Pubmed identfication
  • 25521515
• RefSeq identity
  • NM_000756
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000164474

Gene info

• Identity
  HGNC:2356
• Gene
  CRHBP
• Long gene name
  corticotropin releasing hormone binding protein
• Synonyms gene name
  • corticotropin releasing hormone-binding protein
• Synonyms
  • CRF-BP
  • CRFBP
• GenBank acession
  • X58022
• Locus
  5q13.3
• Discovery year
  1991-08-07
• Entrez gene record
  1393
• Pubmed identfication
  • 8198617
• RefSeq identity
  • NM_001882
• VEGA ID
  OTTHUMG00000102133

Gene info

• Identity
  HGNC:2357
• Gene
  CRHR1
• Long gene name
  corticotropin releasing hormone receptor 1
• Synonyms gene
  • CRHR
• Synonyms
  • CRF-R
  • CRF1
• Synonyms name
  • corticotropin-releasing factor receptor
• GenBank acession
  • L23332
• Locus
  17q21.31
• Discovery year
  1993-12-13
• Entrez gene record
  1394
• Pubmed identfication
  • 7590738
• Classification
  • Corticotropin releasing hormone receptors
• VEGA ID
  OTTHUMG00000178271

Gene info

• Identity
  HGNC:24182
• Gene
  C1QL1
• Long gene name
  complement C1q like 1
• Synonyms gene name
  • complement component 1, q subcomponent-like 1
• Synonyms
  • CRF
  • C1QRF
  • C1QTNF14
  • CTRP14
• GenBank acession
  • AF410771
• Locus
  17q21.31
• Discovery year
  2004-05-06
• Entrez gene record
  10882
• Pubmed identfication
  • 9878755
• RefSeq identity
  • NM_006688
• Classification
  • C1q and TNF related
• VEGA ID
  OTTHUMG00000162944

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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