CLN6 Antibody

• Catalog number
  bs-8017R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CLN6 Primary Polyclonal Antibody
• Also known as
  CLN6 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CLN6
• Specificity
  This is a highly specific antibody against CLN6.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CLN6
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  CLN6, a 311 amino acid protein, has seven predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Ceroid lipofuscinosis, neuronal 6, late infantile, variant; CLN6 protein; FLJ20561; Nclf; Protein CLN6; CLN6_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CLN6  
• Gene symbol
  CLN6
• Short name
  Anti-CLN6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CLN6 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2077
• Gene
  CLN6
• Long gene name
  CLN6 transmembrane ER protein
• Synonyms gene name
  • ceroid-lipofuscinosis, neuronal 6, late infantile, variant
  • CLN6, transmembrane ER protein
• Synonyms
  • FLJ20561
  • HsT18960
  • nclf
• GenBank acession
  • AK000568
• Locus
  15q23
• Discovery year
  1996-10-11
• Entrez gene record
  54982
• Pubmed identfication
  • 9097964
  • 11727201
• RefSeq identity
  • NM_017882
• VEGA ID
  OTTHUMG00000133286
• Locus Specific Databases
  • Neuronal Ceroid Lipofuscinoses; NCL Mutations
  • LRG_832

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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