CD177 Antibody

• Catalog number
  bs-1482R
• Price
  Please ask
• Size
  0.1ml

• Long name
  CD177 Primary Polyclonal Antibody
• Also known as
  CD177 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  CD177/NB1
• Specificity
  This is a highly specific antibody against CD177/NB1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  540-590/818
• Subcellular location
  Cell membrane
• Source
  KLH conjugated synthetic peptide derived from rat CD177
• Gene ID number
  499099
• Swiss Prot
  D3ZCH9
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97% of the caucasian population. against NB1 can be involved in neonatal alloimmune neutropenia (NAN).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NB1 GP;PRV-1;HNA-2a;NB1 glycoprotein;Neutrophil Glycoprotein NB1; RGD1562941; CD177 antigen; Polycythemia rubra vera protein 1; PRV-1; NB1 glycoprotein; NB1 GP; Human neutrophil alloantigen 2a; HNA-2a; CD177; CD177_HUMAN; CD177_MOUSE.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD177  
• Gene symbol
  CD177
• Short name
  Anti-CD177/NB1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  CD177 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  CD177 molecule, CD177 and IDBG-55103 and ENSG00000204936 and 57126, Plasma membranes, Cd177 and IDBG-155436 and ENSMUSG00000052212 and 68891, BT.78171 and IDBG-638968 and ENSBTAG00000002976 and 616350

Gene info

• Identity
  HGNC:30072
• Gene
  CD177
• Long gene name
  CD177 molecule
• Synonyms gene name
  • CD177 antigen
• Synonyms
  • PRV1
  • HNA2A
  • NB1
• Synonyms name
  • polycythemia rubra vera 1
• GenBank acession
  • AF146747
• Locus
  19q13.31
• Discovery year
  2005-08-12
• Entrez gene record
  57126
• Pubmed identfication
  • 10753836
  • 5552408
• RefSeq identity
  • NM_020406
• Classification
  • CD molecules
  • LY6/PLAUR domain containing
• VEGA ID
  OTTHUMG00000185320

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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