CBX4 Antibody
-
Catalog numberbs-17376R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameCBX4 Primary Polyclonal Antibody
-
Also known asCBX4 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenCBX4
-
SpecificityThis is a highly specific antibody against CBX4.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range415-445/560
-
Subcellular locationNucleus
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CBX4
-
Gene ID number8535
-
Swiss ProtO00257
-
Tested ApplicationsWB
-
Recommended dilutionsWB(1:100-1000)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenE3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesPC2; NBP16; E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; hPc2; CBX4
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCBX4
-
Short nameAnti-CBX4
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameCBX4 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetchromobox homolog 4, NBP16 and PC2, CBX4 and IDBG-71254 and ENSG00000141582 and 8535, phosphoprotein binding, nuclei, Cbx4 and IDBG-214671 and ENSMUSG00000039989 and 12418, CBX4 and IDBG-642715 and ENSBTAG00000009782 and
-
Gene info
-
Identity
-
Gene
-
Long gene namechromobox 4
-
Synonyms gene name
- chromobox homolog 4 (Drosophila Pc class)
- chromobox homolog 4
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1998-10-20
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Chromobox family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data