CACNA1G + CACNA1H Antibody
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Catalog number
bs-11984R
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Price
Please ask
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Size
0.1ml
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Long name
CACNA1G + CACNA1H Primary Polyclonal Antibody
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Also known as
CACNA1G + CACNA1H PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
CACNA1G + CACNA1H
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Specificity
This is a highly specific antibody against CACNA1G + CACNA1H.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Subcellular location
Extracellular
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Source
KLH conjugated synthetic peptide derived from CACNA1G + CACNA1H
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Tested Applications
WB, IHC-P, IF(IHC-P)
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Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. There are 2 isoforms of CACNA1H and 14 isoforms if CACNA1G, produced by alternative splicing.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
Cav3.1c; Low voltage activated calcium channel alpha1 3.2 subunit; NBR13; Voltage dependent T type calcium channel subunit alpha 1G; Voltage dependent T type calcium channel subunit alpha 1H; Voltage gated calcium channel subunit alpha Cav3.1; Voltage gated calcium channel subunit alpha Cav3.2; CAC1G_HUMAN; CAC1H_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
CACNA1H, CACNA1G-AS1, CACNA1G
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Short name
Anti-CACNA1G + CACNA1H
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
CACNA1G + CACNA1H Polyclonal Antibody
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Alternative technique
antibodies
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Alternative to gene target
calcium channel, voltage-dependent, T type, alpha 1G subunit, Ca(V)T.1 and Cav3.1 and NBR13, CACNA1G and IDBG-58847 and ENSG00000006283 and 8913, scaffold protein binding, Plasma membranes, Cacna1g and IDBG-208893 and ENSMUSG00000020866 and 12291, CACNA1G and IDBG-638512 and ENSBTAG00000009835 and 282411
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Gene info
Gene info
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Identity
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Gene
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Long gene name
CACNA1G antisense RNA 1
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Synonyms gene name
- CACNA1G antisense RNA 1 (non-protein coding)
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Synonyms
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Locus
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Discovery year
2012-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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