C1orf85 Antibody

• Catalog number
  bs-15078R
• Price
  Please ask
• Size
  0.1ml

• Long name
  C1orf85 Primary Polyclonal Antibody
• Also known as
  C1orf85 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  C1orf85
• Specificity
  This is a highly specific antibody against C1orf85.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C1orf85
• Gene ID number
  112770
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  C1orf85, also known as Lysosomal protein NCU-G1, is a 406 amino acid single-pass membrane protein that is highly glycosylated on its amino-terminal end. Transcription of the gene encoding C1orf85 is activated by TFEB, a transcription factor that specifically recognizes and binds E-box sequences. There are two isoforms of C1orf85 that are produced as a result of alternative splicing events. The C1orf85 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  C1orf85; Chromosome 1 open reading frame 85; Lysosomal protein NCU-G1; NCUG1_HUMAN; PSEC0030; UNQ2553/PRO6182.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  C1orf85  
• Gene symbol
  GLMP
• Short name
  Anti-C1orf85
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  C1orf85 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29436
• Gene
  GLMP
• Long gene name
  glycosylated lysosomal membrane protein
• Synonyms gene
  • C1orf85
• Synonyms gene name
  • chromosome 1 open reading frame 85
• Synonyms
  • MGC31963
  • NCU-G1
• Synonyms name
  • kidney lysosomal membrane protein
• GenBank acession
  • BC011575
• Locus
  1q22
• Discovery year
  2005-05-27
• Entrez gene record
  112770
• Pubmed identfication
  • 18021396
  • 19489740
  • 31661432
• RefSeq identity
  • NM_144580
• VEGA ID
  OTTHUMG00000019789

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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