BNIP3 (Ser95) Antibody

• Catalog number
  bs-12875R
• Price
  Please ask
• Size
  0.1ml

• Long name
  BNIP3 (Ser95) Primary Polyclonal Antibody
• Also known as
  BNIP3 (Ser95) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BNIP3 Ser95
• Specificity
  This is a highly specific antibody against BNIP3 Ser95.
• Modification s
  Phosphorylation
• Modification site s
  Ser95
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human BNIP3 around the phosphorylation site of Ser95
• Gene ID number
  664
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BNIP3 phospho S95; p-BNIP3 phospho S95; BCL2 Adenovirus E1B 19kDa Interacting Protein 3; BCL2/adenovirus E1B 19 kDa protein interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BNIP 3; BNIP3; BNIP3_HUMAN; NIP 3; NIP3.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BNIP3   Ser95  
• Gene symbol
  BNIP3
• Short name
  Anti-BNIP3 Ser95
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  BNIP3 (Ser95) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2/adenovirus E1B 19kDa interacting protein 3, NIP3, BNIP3 and IDBG-93314 and ENSG00000176171 and 664, GTPase binding, nuclei, Bnip3 and IDBG-269444 and ENSMUSG00000078566 and 12176, BNIP3 and IDBG-641206 and ENSBTAG00000017804 and 615342

Gene info

• Identity
  HGNC:1084
• Gene
  BNIP3
• Long gene name
  BCL2 interacting protein 3
• Synonyms gene name
  • BCL2/adenovirus E1B 19kDa interacting protein 3
• Synonyms
  • Nip3
• Synonyms name
  • nineteen kD interacting protein-3
• GenBank acession
  • U15174
• Locus
  10q26.3
• Discovery year
  1997-03-19
• Entrez gene record
  664
• Pubmed identfication
  • 7954800
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000019278

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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