BCL2L1 Antibody
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Catalog numberbs-1336R
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PricePlease ask
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Size0.1ml
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Long nameBCL2L1 Primary Polyclonal Antibody
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Also known asBCL2L1 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenBCL2L1
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SpecificityThis is a highly specific antibody against BCL2L1.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range70-120/233
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Subcellular locationHelical
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BCL2L1
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Gene ID number598
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Swiss ProtQ07817
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Tested ApplicationsWB, ELISA, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), ELISA(1:500-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenPotent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F() activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesBCLX; BCL2L; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; PPP1R52; BCL-XL/S; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; BCL2L1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolBCL2L1-AS1, BCL2L1
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Short nameAnti-BCL2L1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameBCL2L1 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetBCL2-like 1, Bcl-X and bcl-xL and BCL-XL/S and bcl-xS and BCL2L and BCLX and BCLXL and BCLXS and PPP1R52, BCL2L1 and IDBG-63673 and ENSG00000171552 and 598, BH3 domain binding, nuclei, Bcl2l1 and IDBG-209867 and ENSMUSG00000007659 and 12048, BCL2L1 and IDBG-641541 and ENSBTAG00000006526 and 282152
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Gene info
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Identity
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Gene
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Long gene nameBCL2L1 antisense RNA 1
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Locus
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Discovery year2019-07-24
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data