BCL2L1 (804CT19.1.4) Monoclonal Antibody

• Catalog number
  bsm-51229M
• Price
  Please ask
• Size
  0.1ml

• Long name
  BCL2L1 (804CT19.1.4) Monoclonal Antibody
• Also known as
  BCL2L1 (804CT19.1.4) Monoclonal Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BCL2L1
• Specificity
  This is a highly specific antibody against BCL2L1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Monoclonal
• Clone number
  804CT19.1.4
• Source
  Purified His-tagged BCL2L1 protein was used to produced this monoclonal antibody.
• Gene ID number
  598
• Swiss Prot
  Q07817
• Tested Applications
  WB
• Recommended dilutions
  WB(1:1000)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). Isoform Bcl-X(S) promotes apoptosis.
• Purification method
  Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; BCL2L1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  BCL2L1   804CT19   Monoclonal  
• Gene symbol
  BCL2L1-AS1, BCL2L1
• Short name
  Anti-BCL2L1
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  Immunoglobulin G (IgG)1
• Alternative name
  BCL2L1 (804CT19.1.4) Monoclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  BCL2-like 1, Bcl-X and bcl-xL and BCL-XL/S and bcl-xS and BCL2L and BCLX and BCLXL and BCLXS and PPP1R52, BCL2L1 and IDBG-63673 and ENSG00000171552 and 598, BH3 domain binding, nuclei, Bcl2l1 and IDBG-209867 and ENSMUSG00000007659 and 12048, BCL2L1 and IDBG-641541 and ENSBTAG00000006526 and 282152

Gene info

• Identity
  HGNC:40095
• Gene
  BCL2L1-AS1
• Long gene name
  BCL2L1 antisense RNA 1
• Locus
  20q11.21
• Discovery year
  2019-07-24
• Entrez gene record
  105372589
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:992
• Gene
  BCL2L1
• Long gene name
  BCL2 like 1
• Synonyms
  • BCLX
  • BCL2L
  • Bcl-X
  • bcl-xL
  • bcl-xS
  • PPP1R52
• Synonyms name
  • protein phosphatase 1, regulatory subunit 52
• GenBank acession
  • Z23115
• Locus
  20q11.21
• Discovery year
  1997-10-30
• Entrez gene record
  598
• Pubmed identfication
  • 8358789
• RefSeq identity
  • NM_138578
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032192

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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