BAGE2 Antibody

• Catalog number
  bs-9114R
• Price
  Please ask
• Size
  0.1ml

• Long name
  BAGE2 Primary Polyclonal Antibody
• Also known as
  BAGE2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  BAGE2
• Specificity
  This is a highly specific antibody against BAGE2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BAGE2
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  B melanoma antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2; CT2.2; BAGE2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BAGE2  
• Gene symbol
  BAGE2
• Short name
  Anti-BAGE2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  BAGE2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15723
• Gene
  BAGE2
• Long gene name
  BAGE family member 2, pseudogene
• Synonyms gene name
  • B melanoma antigen family, member 2
  • BAGE family member 2
• Synonyms
  • CT2.2
• Synonyms name
  • cancer/testis antigen family 2, member 2
• GenBank acession
  • AF218570
• Locus
  21p11.2
• Discovery year
  2001-06-01
• Entrez gene record
  85319
• Pubmed identfication
  • 12461691
• RefSeq identity
  • NR_169269
• Classification
  • BAGE family
• VEGA ID
  OTTHUMG00000074128

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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