ATG4D Antibody

• Catalog number
  bs-4009R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ATG4D Primary Polyclonal Antibody
• Also known as
  ATG4D PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ATG4D
• Specificity
  This is a highly specific antibody against ATG4D.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  425-474/474
• Subcellular location
  Cytoplasm, Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG4D
• Gene ID number
  84971
• Swiss Prot
  Q86TL0
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  APG4D; AUTL4; APG4-D; Cysteine protease ATG4D; AUT-like 4 cysteine endopeptidase; Autophagin-4; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; ATG4D
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ATG4D  
• Gene symbol
  ATG4D
• Short name
  Anti-ATG4D
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ATG4D Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20789
• Gene
  ATG4D
• Long gene name
  autophagy related 4D cysteine peptidase
• Synonyms gene
  • AUTL4
  • APG4D
• Synonyms gene name
  • AUT-like 4, cysteine endopeptidase (S. cerevisiae)
  • APG4 autophagy 4 homolog D (S. cerevisiae)
  • ATG4 autophagy related 4 homolog D (S. cerevisiae)
  • autophagy related 4D, cysteine peptidase
• Synonyms
  • APG4-D
• GenBank acession
  • AJ312332
• Locus
  19p13.2
• Discovery year
  2003-04-11
• Entrez gene record
  84971
• Pubmed identfication
  • 12446702
• RefSeq identity
  • NM_032885
• Classification
  • MicroRNA protein coding host genes
  • Autophagy related
• VEGA ID
  OTTHUMG00000180582

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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