ASAH1 Antibody

• Catalog number
  bs-12976R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ASAH1 Primary Polyclonal Antibody
• Also known as
  ASAH1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ASAH1
• Specificity
  This is a highly specific antibody against ASAH1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acid ceramidase subunit beta
• Gene ID number
  427
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  AC; ACDase; Acid CDase; Acid ceramidase; Acid ceramidase precursor; Acid ceramidase subunit beta; Acylsphingosine deacylase; ASAH 1; ASAH; ASAH1; ASAH1_HUMAN; FLJ21558; FLJ22079; N acylsphingosine amidohydrolase acid ceramidase 1; N acylsphingosine amidohydrolase 1; N acylsphingosine amidohydrolase; N-acylsphingosine amidohydrolase; PHP; PHP32; Putative 32 kDa heart protein.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ASAH1  
• Gene symbol
  ASAH1-AS1, ASAH1
• Short name
  Anti-ASAH1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ASAH1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55603
• Gene
  ASAH1-AS1
• Long gene name
  ASAH1 antisense RNA 1
• Locus
  8p22
• Discovery year
  2021-06-07
• Entrez gene record
  101929066
• RefSeq identity
  • NR_125429
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:735
• Gene
  ASAH1
• Long gene name
  N-acylsphingosine amidohydrolase 1
• Synonyms gene
  • ASAH
• Synonyms gene name
  • N-acylsphingosine amidohydrolase (acid ceramidase)
• Synonyms
  • AC
  • PHP32
  • FLJ21558
  • ACDase
• Synonyms name
  • acylsphingosine deacylase
  • acid ceramidase
• GenBank acession
  • U70063
• Locus
  8p22
• Discovery year
  1997-08-22
• Entrez gene record
  427
• Pubmed identfication
  • 8955159
  • 10610716
• RefSeq identity
  • NM_004315
• VEGA ID
  OTTHUMG00000096997

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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