ARRDC3 Antibody

• Catalog number
  bs-8077R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ARRDC3 Primary Polyclonal Antibody
• Also known as
  ARRDC3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ARRDC3
• Specificity
  This is a highly specific antibody against ARRDC3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARRDC3 corresponding to amino acids 178-215.
• Gene ID number
  57561
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The arrestins are a family of proteins that are important for regulating signal transduction within cells. Arrestins are part of a conserved two step mechanism for regulating the activity of G-protein coupled receptors (GPCRs). In response to a stimulus, GPCRs activate a heterotrimeric G protein. In order to turn off this response, or adapt to a constant stimulus, activated receptors need to be silenced. The first step is phosphorylation by a class of serine/threonine kinases called G protein coupled receptor kinases (GRKs). This phosphorylation specifically marks the activated receptor for arrestin binding. Once arrestin is bound to the receptor it is unable to signal further. Recent research continues to expand the known actions of arrestins, which can bind to other classes of receptors and can directly activate signaling pathways on their own. Different arrestins (visual arrestin (or Arrestin 1), beta-arrestin 1 (or Arrestin 2) and beta-arrestin 2 (or Arrestin 3) can reduce the activity of their target GPCRs in several different ways.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ARRDC 3; Arrestin domain containing protein 3; KIAA1376; Thioredoxin binding protein 2 like inducible membrane; TLIMP; ARRD3_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ARRDC3  
• Gene symbol
  ARRDC3-AS1, ARRDC3
• Short name
  Anti-ARRDC3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ARRDC3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:44145
• Gene
  ARRDC3-AS1
• Long gene name
  ARRDC3 antisense RNA 1
• Synonyms gene name
  • ARRDC3 antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC043415
• Locus
  5q14.3
• Discovery year
  2012-06-30
• Entrez gene record
  100129716
• RefSeq identity
  • NR_027435
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000189546

Gene info

• Identity
  HGNC:29263
• Gene
  ARRDC3
• Long gene name
  arrestin domain containing 3
• Synonyms
  • KIAA1376
  • TLIMP
• Synonyms name
  • alpha-arrestin 3
  • TBP-2-like inducible membrane protein
• GenBank acession
  • AB037797
• Locus
  5q14.3
• Discovery year
  2004-02-11
• Entrez gene record
  57561
• Pubmed identfication
  • 10718198
  • 19605364
• RefSeq identity
  • NM_020801
• Classification
  • Alpha arrestins
• VEGA ID
  OTTHUMG00000162616

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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