ARHGAP17 Antibody
-
Catalog numberbs-2304R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameARHGAP17 Primary Polyclonal Antibody
-
Also known asARHGAP17 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenARHGAP17
-
SpecificityThis is a highly specific antibody against ARHGAP17.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic peptide derived from fruit fly ARHGAP17/Nadrin
-
Gene ID number55114
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym namesARHGAP17; NADRIN; Neuron associated developmentally regulated protein; Rho GTPase activating protein 17; RhoGAP interacting with CIP4 homologs protein 1; RICH 1; RICH1; WBP15; MST066; MST110; MSTP038; PP367; PP4534; Rho type GTPase activating protein 17; RhoGAP interacting with CIP4 homologs 1; RICH1B.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolARHGAP17
-
Short nameAnti-ARHGAP17
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameARHGAP17 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Alternative to gene targetRho GTPase activating protein 17, ARHGAP17 and IDBG-21389 and ENSG00000140750 and 55114, SH3 domain binding, Cell surfaces, Arhgap17 and IDBG-209112 and ENSMUSG00000030766 and 70497, ARHGAP17 and IDBG-638696 and ENSBTAG00000020043 and 504245
-
Gene info
-
Identity
-
Gene
-
Long gene nameRho GTPase activating protein 17
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2004-04-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- N-BAR domain containing
- AH/BAR family Rho GTPase activating proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data