APBB1 (Ser175) Antibody

• Catalog number
  bs-5165R
• Price
  Please ask
• Size
  0.1ml

• Long name
  APBB1 (Ser175) Primary Polyclonal Antibody
• Also known as
  APBB1 (Ser175) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  APBB1 Ser175
• Specificity
  This is a highly specific antibody against APBB1 Ser175.
• Modification s
  Phosphorylation
• Modification site s
  Ser175
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human APBB1 around the phosphorylation site of Ser175 [LS(p-S)PP]
• Gene ID number
  322
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Adaptor protein FE65a2; Amyloid beta A4 precursor protein binding family B member 1; Amyloid beta A4 precursor protein binding family B; Amyloid beta A4 precursor protein binding family B member 1; Amyloid beta precursor protein binding family B member 1; APBB 1; APBB1; FE 65; Fe65 protein; MGC 9072; MGC9072; Protein Fe65; RIR; Stat like protein; Fe-65 Protein; APBB1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  APBB1   Ser175  
• Gene symbol
  APBB1
• Short name
  Anti-APBB1 Ser175
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  APBB1 (Ser175) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65), FE65 and MGC:9072 and RIR, APBB1 and IDBG-28785 and ENSG00000166313 and 322, proline-rich region binding, nuclei, Apbb1 and IDBG-204734 and ENSMUSG00000037032 and 11785, APBB1 and IDBG-634164 and ENSBTAG00000015655 and 505096

Gene info

• Identity
  HGNC:581
• Gene
  APBB1
• Long gene name
  amyloid beta precursor protein binding family B member 1
• Synonyms gene
  • RIR
• Synonyms gene name
  • amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
• Synonyms
  • Fe65
• GenBank acession
  • L77864
• Locus
  11p15.4
• Discovery year
  1997-03-27
• Entrez gene record
  322
• Pubmed identfication
  • 8955346
  • 8894693
• RefSeq identity
  • NM_001164
• VEGA ID
  OTTHUMG00000165454

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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