Ankyrin B Antibody

• Catalog number
  bs-6967R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Ankyrin B Primary Polyclonal Antibody
• Also known as
  Ankyrin B PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Ankyrin B
• Specificity
  This is a highly specific antibody against Ankyrin B.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ankyrin B
• Gene ID number
  55024
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain, and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin B, or brain Ankyrin is predominantly expressed in the plasma membrane of neurons as well as glial cells throughout the brain. Two transcripts have been described with alternative splicing resulting in additional isoforms. The Ankyrin B protein associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin B is required for coordinated assembly of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor at transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ANK-2; Ank2; ANK2_HUMAN; Ankyrin 2; Ankyrin 2 brain; Ankyrin B; Ankyrin nonerythroid; ANKYRIN, NEURONAL; Ankyrin-2; Ankyrin-B; Brain ankyrin; Non-erythroid ankyrin
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Ankyrin  
• Gene symbol
  ANKRD44, SOWAHB, POTEB
• Short name
  Anti-Ankyrin B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Ankyrin B Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25259
• Gene
  ANKRD44
• Long gene name
  ankyrin repeat domain 44
• Synonyms
  • PP6-ARS-B
• Synonyms name
  • protein phosphatase 6 ankyrin repeat subunit B
• GenBank acession
  • AK097086
• Locus
  2q33.1
• Discovery year
  2005-05-29
• Entrez gene record
  91526
• Pubmed identfication
  • 18186651
• RefSeq identity
  • NM_153697
• Classification
  • Ankyrin repeat domain containing
  • Protein phosphatase 6 regulatory subunits
• VEGA ID
  OTTHUMG00000154411

Gene info

• Identity
  HGNC:32958
• Gene
  SOWAHB
• Long gene name
  sosondowah ankyrin repeat domain family member B
• Synonyms gene
  • ANKRD56
• Synonyms gene name
  • ankyrin repeat domain 56
• Locus
  4q21.1
• Discovery year
  2006-07-12
• Entrez gene record
  345079
• Pubmed identfication
  • 22234889
• RefSeq identity
  • NM_001029870
• Classification
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000160876

Gene info

• Identity
  HGNC:33734
• Gene
  POTEB
• Long gene name
  POTE ankyrin domain family member B
• Synonyms gene
  • A26B1
• Synonyms gene name
  • ANKRD26-like family B, member 1
  • POTE ankyrin domain family, member B
• Synonyms
  • POTE15
  • POTE-15
  • CT104.5
• Synonyms name
  • cancer/testis antigen family 104, member 5
• GenBank acession
  • AY465170
• Locus
  15q11.2
• Discovery year
  2007-11-21
• Entrez gene record
  100996331
• RefSeq identity
  • NM_207355
• Classification
  • POTE ankyrin domain containing
• VEGA ID
  OTTHUMG00000171734

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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