Amyloid Precursor Protein (T743) Antibody
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Catalog numberbs-3028R
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PricePlease ask
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Size0.1ml
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Long nameAmyloid Precursor Protein (T743) Antibody
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Also known asAmyloid Precursor Protein (T743) Antibody
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenAmyloid Precursor Protein Thr743
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SpecificityThis is a highly specific antibody against Amyloid Precursor Protein Thr743.
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Modification sPhosphorylation
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Modification site sThr743
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceKLH conjugated synthetic phosphopeptide derived from human APP around the phosphorylation site of Thr743
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Gene ID number351
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesAmyloid Precursor Protein phospho Thr743; Amyloid Precursor Protein phospho Thr743; p-Amyloid Precursor Protein phospho Thr743; APP Thr743;
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionPrecursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.
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French translationanticorps
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Gene target
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Short nameAnti-Amyloid Precursor Protein Thr743
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameAmyloid Precursor Protein (T743) Antibody
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Alternative techniqueantibodies
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MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data