Adenylosuccinate Lyase Antibody

• Catalog number
  bs-6352R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Adenylosuccinate Lyase Antibody
• Also known as
  Adenylosuccinate Lyase Antibody
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Adenylosuccinate Lyase
• Specificity
  This is a highly specific antibody against Adenylosuccinate Lyase.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Adenylosuccinase; Adenylosuccinate lyase; ADSL; AMPS; ASase; ASL; PUR8_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Adenylosuccinate   Lyase  
• Gene symbol
  ADSL
• Short name
  Anti-Adenylosuccinate Lyase
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Adenylosuccinate Lyase Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:291
• Gene
  ADSL
• Long gene name
  adenylosuccinate lyase
• GenBank acession
  • X65867
• Locus
  22q13.1
• Discovery year
  1986-01-01
• Entrez gene record
  158
• Pubmed identfication
  • 8404037
• RefSeq identity
  • NM_000026
• Classification
  • Purinosome
• VEGA ID
  OTTHUMG00000166425
• Locus Specific Databases
  • Adenylosuccinate Lyase Mutations Database Home Page

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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