ADAM17 (Thr735) Antibody

• Catalog number
  bs-12447R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ADAM17 (Thr735) Primary Polyclonal Antibody
• Also known as
  ADAM17 (Thr735) PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ADAM17 Thr735
• Specificity
  This is a highly specific antibody against ADAM17 Thr735.
• Modification s
  Phosphorylation
• Modification site s
  Thr735
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human ADAM17 around the phosphorylation site of Thr735
• Gene ID number
  6868
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ADAM17 phospho T735; p-ADAM17 phospho T735; p-CD156bphospho T735;A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 tumor necrosis factor, alpha, converting enzyme.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADAM17   Thr735  
• Gene symbol
  ADAM17
• Short name
  Anti-ADAM17 Thr735
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ADAM17 (Thr735) Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  ADAM metallopeptidase domain 17, ADAM18 and CD156B and CSVP and NISBD and TACE, ADAM17 and IDBG-27788 and ENSG00000151694 and 6868, PDZ domain binding, Cell surfaces, Adam17 and IDBG-130508 and ENSMUSG00000052593 and 11491, ADAM17 and IDBG-638333 and ENSBTAG00000001141 and 517541

Gene info

• Identity
  HGNC:195
• Gene
  ADAM17
• Long gene name
  ADAM metallopeptidase domain 17
• Synonyms gene
  • TACE
• Synonyms gene name
  • tumor necrosis factor, alpha, converting enzyme
• Synonyms
  • cSVP
  • CD156B
• Synonyms name
  • cartilage snake venom-like protease
  • TNF-alpha convertase enzyme
  • a disintegrin and metalloproteinase 17
• GenBank acession
  • U69611
• Locus
  2p25.1
• Discovery year
  1997-04-10
• Entrez gene record
  6868
• Pubmed identfication
  • 9034190
  • 9574564
• Classification
  • ADAM metallopeptidase domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000090425
• Locus Specific Databases
  • LRG_1203

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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