ACE Antibody

• Catalog number
  bs-0439R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ACE Primary Polyclonal Antibody
• Also known as
  ACE PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ACE
• Specificity
  This is a highly specific antibody against ACE.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Cytoplasm, Secreted, Cell membrane
• Source
  KLH conjugated synthetic peptide derived from cat ACE1
• Gene ID number
  101094061
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Angiotensin Converting Enzyme 1; ACE; ACE-T; Dipeptidyl carboxy peptidase 1; Kininase II; ACE-1; testis-specic isoform precursor; ACE1; Angiotensin converting enzyme testis specic isoform; Carboxycathepsin; CD 143; DCP 1; Dipeptidyl carboxypeptidase 1; MVCD3; Peptidase P; Peptidyl dipeptidase A; Testicular ECA
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ACE  
• Gene symbol
  ACE
• Short name
  Anti-ACE
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ACE Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  Angiotensin-converting enzyme; Uncharacterized protein, ACE and IDBG-728302 and ENSG00000264813 and, peptidyl-dipeptidase activity, Plasma membranes

Gene info

• Identity
  HGNC:2707
• Gene
  ACE
• Long gene name
  angiotensin I converting enzyme
• Synonyms gene
  • DCP1
• Synonyms gene name
  • angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
• Synonyms
  • ACE1
  • CD143
• Synonyms name
  • peptidyl-dipeptidase A
• GenBank acession
  • J04144
• Locus
  17q23.3
• Discovery year
  1989-06-06
• Entrez gene record
  1636
• Pubmed identfication
  • 2554286
  • 10319862
• RefSeq identity
  • NM_000789
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000154927

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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