5HTR2C Antibody

• Catalog number
  bs-2959R
• Price
  Please ask
• Size
  0.1ml

• Long name
  5HTR2C Primary Polyclonal Antibody
• Also known as
  5HTR2C PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  5HTR2C
• Specificity
  This is a highly specific antibody against 5HTR2C.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 5HTR2C
• Gene ID number
  3358
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  5 Hydroxytryptamine 2C receptor; 5-HT-1C; 5-ht-1c receptor; 5-HT-2C; 5-HT1C; 5-HT2C; 5-HTR2C; 5-hydroxytryptamine serotonin receptor 2C, G protein-coupled; 5-hydroxytryptamine receptor 1C; 5-hydroxytryptamine receptor 2C; 5HT1C; 5HT2C; 5HT2C_HUMAN; 5HTR2C; 5Hydroxytryptamine 2C receptor; Htr1c; HTR2C; serotonin 1c receptor; serotonin 2c receptor; Serotonin 5-HT-2C receptor; Serotonin receptor 2C.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  5HTR2C  
• Gene symbol
  HTR2C
• Short name
  Anti-5HTR2C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  5HTR2C Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5295
• Gene
  HTR2C
• Long gene name
  5-hydroxytryptamine receptor 2C
• Synonyms gene
  • HTR1C
• Synonyms gene name
  • 5-hydroxytryptamine (serotonin) receptor 2C
  • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
• Synonyms
  • 5-HT2C
  • 5HTR2C
• Locus
  Xq23
• Discovery year
  1994-08-29
• Entrez gene record
  3358
• Pubmed identfication
  • 7895773
• RefSeq identity
  • NM_000868
• Classification
  • 5-hydroxytryptamine receptors, G protein-coupled
  • Small nucleolar RNA protein coding host genes
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000022226
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_1009

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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