5HT2B Receptor/SR-2B Antibody
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Catalog numberbs-12050R
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PricePlease ask
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Size0.1ml
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Long name5HT2B Receptor/SR-2B Primary Polyclonal Antibody
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Also known as5HT2B Receptor/SR-2B PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target Antigen5HT2B Receptor/SR-2B
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SpecificityThis is a highly specific antibody against 5HT2B Receptor/SR-2B.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human 5HT2B Receptor/SR-2B
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenSerotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names5 HT 2B; 5 HT 2B receptor; 5 HT2B; 5 HT2B; 5 hydroxytryptamine serotonin receptor 2B; 5 hydroxytryptamine serotonin receptor 2B G protein coupled; 5 hydroxytryptamine 2B receptor; 5 hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; 5-hydroxytryptamine receptor 2B; 5HT2B; 5HT2B_HUMAN; 5HT2F; Htr 2b; Htr2b; NP75 protein; SEROTONIN 5HT2B RECEPTOR; Serotonin receptor 2B; Stomach fundus serotonin receptor.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolIGHD2OR15-2B, MSR1, CXCL3, MEGF10, MARCO, EIF2B3, SRPRB, SIGMAR1, SNCG, SNORD3B-2
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Short nameAnti-5HT2B Receptor/SR-2B
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative name5HT2B Receptor/SR-2B Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy diversity 2/OR15-2B (non-functional)
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Synonyms gene name
- immunoglobulin heavy diversity 2/OR15-2B
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemacrophage scavenger receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-08-07
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Pubmed identfication
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Classification
- CD molecules
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-X-C motif chemokine ligand 3
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Synonyms gene
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Synonyms gene name
- GRO3 oncogene
- chemokine (C-X-C motif) ligand 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-05-21
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Entrez gene record
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Pubmed identfication
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemultiple EGF like domains 10
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Synonyms gene name
- multiple EGF-like-domains 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemacrophage receptor with collagenous structure
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameeukaryotic translation initiation factor 2B subunit gamma
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Synonyms gene name
- eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD)
- eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-10-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSRP receptor subunit beta
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Synonyms gene name
- signal recognition particle receptor, B subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesigma non-opioid intracellular receptor 1
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Synonyms gene
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Synonyms gene name
- opioid receptor, sigma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-03-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesynuclein gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-07
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 3B-2
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Synonyms
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Synonyms name
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Locus
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Discovery year2006-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data