ZNF312B/FEZF1 Antibody, Biotin Conjugated

• Catalog number
  bs-11498R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  ZNF312B/FEZF1 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ZNF312B/FEZF1
• Specificity
  This is a highly specific antibody against ZNF312B/FEZF1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human ZNF312B
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Olfactory sensory neurons contain olfactory receptors, which are G protein-coupled receptor proteins that localize to the cilia and display affinity for and bind to a variety of odor molecules. Olfactory neurons send their axons from the olfactory epithelium to the olfactory bulb, which is covered by the CNS basal lamina. FEZF1 (Fez family zinc finger protein 1), also known as Forebrain Embryonic Zinc Finger and Zinc finger protein 312B, is a 475 amino acid nuclear protein that is expressed in the olfactory epithelium and hypothalamus of mice. In FEZF1-deficient mice, axons of olfactory neurons do not reach the olfactory bulb, suggesting that FEXF1 is required for the penetration of olfactory axons though the basal lamina before innervation of the olfactory bulb. When FEZF1 translocates to the nucleus, it induces KRAS overexpression, resulting in activation of ERK-signaling. Overexpression of FEZF1 leads to accelerated proliferation in cultured cells and increased tumor mass in mice. There are three isoforms of FEZF1 that are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  FEZ; FEZ family zinc finger 1; Fez family zinc finger protein 1; fez like; fezf1; FEZF1_HUMAN; Zinc finger protein 312 like; Zinc finger protein 312B.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  ZNF312B/FEZF1   Conjugated  
• Gene symbol
  FEZF1, FEZF1-AS1
• Short name
  Anti-ZNF312B/FEZF1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-ZNF312B/FEZF1 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:22788
• Gene
  FEZF1
• Long gene name
  FEZ family zinc finger 1
• Synonyms gene
  • ZNF312B
• Synonyms gene name
  • zinc finger protein 312B
• GenBank acession
  • AY726588
• Locus
  7q31.32
• Discovery year
  2006-08-14
• Entrez gene record
  389549
• RefSeq identity
  • NM_001024613
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000157091

Gene info

• Identity
  HGNC:41001
• Gene
  FEZF1-AS1
• Long gene name
  FEZF1 antisense RNA 1
• Synonyms gene name
  • FEZF1 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AK057037
• Locus
  7q31.32
• Discovery year
  2012-06-30
• Entrez gene record
  154860
• Pubmed identfication
  • 26848625
  • 28209170
  • 29864963
• RefSeq identity
  • NR_036484
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000157095

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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