WNT5A Antibody, Cy7 Conjugated
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Catalog number
bs-1948R-Cy7
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Price
Please ask
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Size
0.1ml
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Long name
WNT5A Polyclonal Antibody, Cy7 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy7
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
WNT5A
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Specificity
This is a highly specific antibody against WNT5A.
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Modification
Unmodified
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Modification site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen_range
330-380/381
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Subcellular location
Secreted
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Source
KLH conjugated synthetic peptide derived from human WNT5A
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Gene ID number
7474
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Swiss Prot
P41221
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat, Dog
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
743nm/767nm
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Synonyms
hWNT5A; Protein Wnt-5a; WNT5A
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugation
Cy7
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French translation
anticorps
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Gene target
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Gene symbol
WNT5A, WNT5A-AS1
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Short name
Anti-WNT5A
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy7
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Alternative name
Anti-WNT5A PAb Cy7
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Alternative technique
antibodies
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Alternative to gene target
wingless-type MMTV integration site family, member 5A, hWNT5A, WNT5A and IDBG-40713 and ENSG00000114251 and 7474, receptor a this GO nist activity, Extracellular, Wnt5a and IDBG-141666 and ENSMUSG00000021994 and 22418, BT.88484 and IDBG-645372 and ENSBTAG00000020221 and 530005
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Gene info
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Identity
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Gene
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Long gene name
Wnt family member 5A
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Synonyms gene name
- wingless-type MMTV integration site family, member 5A
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1993-07-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
WNT5A antisense RNA 1
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Synonyms gene name
- WNT5A antisense RNA 1 (non-protein coding)
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Locus
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Discovery year
2011-07-25
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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