WNK3 protein Antibody, Cy7 Conjugated
-
Catalog number
bs-1945R-Cy7
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
WNK3 protein Polyclonal Antibody, Cy7 Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
Cy7
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
WNK3 protein
-
Specificity
This is a highly specific antibody against WNK3 protein.
-
Modification
Unmodified
-
Modification site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen_range
475-520/1800
-
Subcellular location
Cytoplasm
-
Source
KLH conjugated synthetic peptide derived from human WNK3 protein
-
Gene ID number
65267
-
Swiss Prot
Q9BYP7
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
743nm/767nm
-
Synonyms
PRKWNK3; Serine/threonine-protein kinase WNK3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; WNK3; KIAA1566
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
-
Additional conjugation
Cy7
-
French translation
anticorps
-
Gene target
-
Gene symbol
WNK3
-
Short name
Anti-WNK3 protein
-
Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
Isotype
Immunoglobulin G (IgG)
-
Label
Cy7
-
Alternative name
Anti-WNK3 protein PAb Cy7
-
Alternative technique
antibodies
-
Alternative to gene target
WNK lysine deficient protein kinase 3, WNK3 and IDBG-71035 and ENSG00000196632 and 65267, transferase activity, Cell surfaces, Wnk3 and IDBG-178902 and ENSMUSG00000041245 and 279561, WNK3 and IDBG-637533 and ENSBTAG00000023182 and
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products