VEGF receptor 2 (Tyr1059) Antibody, Biotin Conjugated
-
Catalog numberbs-3467R-Biotin
-
PricePlease ask
-
Size0.1ml
-
-
Long nameVEGF receptor 2 (Tyr1059) Antibody, Biotin Conjugated
-
CategoryConjugated Primary Antibodies
-
ConjugationBiotin
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenVEGF receptor 2 Tyr1059
-
SpecificityThis is a highly specific antibody against VEGF receptor 2 Tyr1059.
-
ModificationPhosphorylation
-
Modification siteTyr1059
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human VEGF receptor 2 around the phosphorylation site of Tyr1059
-
Gene ID number3791
-
Tested applicationsWB, IHC-P
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500)
-
CrossreactivityHuman, Mouse, Rat
-
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen backgroundVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation EmissionN/A
-
SynonymsVEGFR2Tyr1059; VEGFR2Y1059; p-VEGFR2Tyr1059; p-VEGFR2Y1059; CD309; CD309 antigen; Fetal liver kinase 1; FLK-1; FLK1; KDR; Kinase insert domain receptor a type III receptor tyrosine kinase; Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
-
Additional conjugationBiotinylated
-
DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
French translationanticorps
-
Gene target
-
Gene symbolVEGFA, VEGFC, VEGFD
-
Short nameAnti-VEGF receptor 2 Tyr1059
-
TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
IsotypeImmunoglobulin G (IgG)
-
LabelBiotin
-
Alternative nameAnti-VEGF receptor 2 Tyr1059 PAb Biotin
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene namevascular endothelial growth factor A
-
Synonyms gene
-
Synonyms gene name
- vascular endothelial growth factor
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1994-01-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- VEGF family
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namevascular endothelial growth factor C
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1996-10-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- VEGF family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namevascular endothelial growth factor D
-
Synonyms gene
-
Synonyms gene name
- c-fos induced growth factor (vascular endothelial growth factor D)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1997-03-27
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- VEGF family
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data